On the occasions when I have pondered over men's various activities, the dangers and worries they are exposed to at court or at war, from which so many quarrels, passions, risky, often ill-conceived actions and so on are born, I have often said that man's unhappiness springs from one thing alone, his incapacity to stay quietly in one room. A man wealthy enough for life's needs would never leave home to go to sea or beseige some fortress if he knew how to stay at home and enjoy it....~Blaise Pascal, Penseés, "Diversion," 136.
It is generally shortened to: All mankind's troubles are caused by one single thing, which is their inability to sit quietly in a room.
* * * Since we are destined to live out our lives in the prison of our minds, our one duty is to furnish it well~Peter Ustinov